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Arthrosamid®: Long-lasting Pain Relief for Knee Osteoarthritis

A single-injection, non-biodegradable hydrogel treatment designed to provide lasting relief from knee pain — without the need for surgery.

What is Arthrosamid®?

Arthrosamid® is an innovative non-biodegradable hydrogel technology. It is a 2.5% cross-linked polyacrylamide and 97.5% water, specifically developed to treat the symptoms of knee osteoarthritis.

Unlike traditional treatments that are absorbed by the body, Arthrosamid® integrates into the synovial tissue of the joint capsule, offering a permanent cushioning effect that reduces pain and improves mobility.

  • First and only approved injectable implant for knee OA
  • Single procedure performed under local anesthesia
  • Significant, long-lasting reduction in knee pain

"A revolutionary treatment in managing knee health."

How Arthrosamid® Works

01
Initial Injection

Once Injected, Arthrosamid® disperses in the synovial fluid and is cleared by the normal intimal transport mechanisms into the synovial subintima.

02
Permanent Restoration

The physical presence of Arthrosamid® in the synovial membrane restores synovial elasticity, reducing OA drivers and providing lasting pain relief.

Why Choose Arthrosamid?

Proven Results

Supported by more than two decades of research, Arthrosamid® is proven to be safe and effective for long-term pain relief.

Long-lasting

Arthrosamid® is designed to provide significant pain reduction that lasts for years, not just months like HA injections.

Non-Surgical

A simple, one-step procedure performed under local anesthesia by a qualified physician—without hospital stays.

The Treatment Journey

We guide you through every step of the process to ensure the best possible outcome for your mobility and comfort.

4 Simple Steps
01
Consultation

Speak with our specialist to determine if Arthrosamid is the right solution for your specific knee condition.

02
The Procedure

A single injection performed in-clinic under local and anesthesia and ultrasound guidance. The process typically takes less than 30 minutes.

03
Recovery

Return home the same day. Most patients can resume normal daily activities within 24 to 48 hours.

04
Lasting Relief

Experience a gradual reduction in pain and stiffness over the coming weeks, lasting for years.

Benefits & FAQ

How long will my pain be reduced?

Polyacrylamide does not degrade and can provide significant relief for up to 5 years. Patients typically begin to experience pain relief within 4-12 weeks.

How often can I have this done?

Repeat injections can be performed indefinitely.

Who cannot have this procedure done?

Any patient with an active infection (body-wide or near injection site) or a recent knee arthroscopy within the last 6 months should not undergo this treatment.

What should I do in advance?

You will be prescribed antibiotics prior to your procedure. Please ensure you take these 1-6 hours before the injection to avoid potential infection.

What do I need to know about the injection later on?

If you are scheduled to have a surgical or dental procedure in the future, you should tell the treating doctor that you have a permanent hydrogel implant as this may require prophylactic antibiotic therapy.

Can I drive afterwards?

For most injections, people can drive afterwards. Nonetheless, bringing a driver is always a good idea just in case. We ask all patients to remain in the clinic waiting room for a minimum of 15 minutes afterwards to observe for any adverse reactions.

Can I play sports afterwards?

This depends on the type of sport and intensity, but we generally recommend taking it easy for 2 days as post-injection flares may occur. If steroid was provided, this takes effect after day 2. Overall, please be mindful with anything you do and listen to your body.

How much does this cost?​

Please see our fees and financing or contact us for more information.

Safety & Side Effects

Common, but not severe
  • Pain after injection: A post-injection flare occurs in up to 11% of patients (Puttick 1995; Pullman-Moor 2002). Similar to steroid injections, it usually settles within 2 days. Application of ice and simple pain medications (e.g. Tylenol, Advil) can help, if desired.
  • Pain during procedure: The skin is the most sensitive part when it comes to any injection. We minimize this by using local anesthetic and/or a vapocoolant spray on the skin. Pain associated with the injection is usually brief and well-tolerated.
Not common, but potentially severe
  • Infection: When a needle is passed through the skin into the body, there is a very small chance of introducing a joint infection. The chance of this occurring is extremely low, less than 0.002%, or equivalent to being struck by a car as a pedestrian and experiencing a catastrophic event. To minimize this risk, we not only follow the WHO minimum best practice standards for injections, but use sterile gloves, sterile ultrasound probe covers, and sterile ultrasound gel.
  • Allergy: A swelling reaction to the local injectate can occur at the site of administration. We ask all patients to remain in the clinic waiting room afterwards for a minimum of 15 minutes to observe for any adverse reactions to the medication. There have been no reported allergic reactions to Arthrosamid itself.
  • Bleeding: This is a greater risk if you have a known bleeding disorder or are taking blood thinners. By using ultrasound guidance, there is less “poking” around to get to the target tissue of interest, and thus less theoretical risk of bleeding. Pressure is maintained over the skin afterwards to reduce bleeding.

Ready to reclaim your active lifestyle?

Book a consultation at The Ability Clinic today and find out if Arthrosamid® is the right choice for your knee health.

755 Queensway East

Mississauga ON L4Y 4C5

REHABILITATION SERVICES

Unit 303: Physiotherapy, Massage Therapy,
Chiropractic, Custom Bracing, DEXA Body Scans

Mon, Wed, Fri : 8 am to 7 pm
Tues, Thurs : 8 am to 5 pm
Sat to Sun : Closed

MEDICAL SERVICES

Unit 303: Rheumatology, Neurology, Psychiatry, Lifestyle Medicine
Unit 304: Physical Medicine, NCS/EMG, US-Guided Injections

Mon to Fri : 8 am to 5 pm
Sat to Sun : Closed
(Hours and availability may vary)

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